The effects of soy tempeh diet on endocrine and reproductive function / Khairunnisa Zuradi

The aim of the study was to find out whether soy tempeh diet would significantly affect the male endocrine and reproductive system. The result shows that daily diet of soy tempeh significantly reduced TSH, T3 and testosterone hormone. Tempeh diet also significantly caused a delay in male sexual maturation (puberty) by about 2.64 ± 1.43 days in the treated group (42 ± 1.57 days) compared to controls (39.36 ± 1.28 days). The observed effects by soy tempeh diet may be attributed to its genistein content. Genistein disrupts reproductive function by disrupting enzyme systems that regulate testosterone synthesis and the synthesis of thyroid hormones.