Design and analysis of DNA sequence alignment module using Smith-Waterman scoring pattern: article / Wan Abdul Qayyum Moh Salleh and A.K. Halim

Moh Salleh, Wan Abdul Qayyum and A.K., Halim (2013) Design and analysis of DNA sequence alignment module using Smith-Waterman scoring pattern: article / Wan Abdul Qayyum Moh Salleh and A.K. Halim. pp. 1-8.

Abstract

This project is to design and analyze the DNA sequence alignment module using Smith-Waterman scoring patterns. The main objective is to create SW pattern in matrix using Excel based equation. The second objective is to construct the module for SW sequence alignment using the matrix pattern. One of the major problems rose from DNA sequence alignment is the speed and accuracy. The computational demand needed to explore for analyze the data faster and accurate in these databases is quickly becoming a great concern. This system will be using Verilog language and optimize it using pattern recognition in order to overcome the accuracy issues. The system optimizes the aligning DNA fragment using Smith-Waterman algorithm with a pattern recognition algorithm. FPGA design, synthesis and simulation are done using the Xilinx ISE software and obtain the RTL schematic as well as the waveform of the module. Synopsys tools are used for analysis the project in ASIC design. VCS for verification the design for further process in ASIC design tools are used. Design Compiler is for resynthesize and remodelling the design with setup constraints. Static timing analysis using Prime Time is for advance timing analysis. Based on the result obtained, the minimum frequency that is suitable for this project is 50 MHz. The average power consumption for normal compile high compile and ultra-compile are 53 uW, 52.8 uW and 49.8 uW. The average Cell area for normal compile high compile and ultra-compile are 18700 um2, 18280 um2 and 9532 um2.

Metadata

Item Type: Article
Creators:
Creators
Email / ID Num.
Moh Salleh, Wan Abdul Qayyum
wanabdulqayyum@gmail.com
A.K., Halim
UNSPECIFIED
Subjects: T Technology > TK Electrical engineering. Electronics. Nuclear engineering > Telecommunication > Computer networks. General works. Traffic monitoring
Divisions: Universiti Teknologi MARA, Shah Alam > Faculty of Electrical Engineering
Page Range: pp. 1-8
Keywords: DNA sequence, smith-waterman scoring patterns, ASIC design tool
Date: July 2013
URI: https://ir.uitm.edu.my/id/eprint/115609
Edit Item
Edit Item

Download

[thumbnail of 115609.pdf] Text
115609.pdf

Download (531kB)

ID Number

115609

Indexing

Statistic

Statistic details