Synthesis of benzothiazole derivative compounds with potential anti bacterial activities / Noor Arfiqah Ahmad

Inappropriate use of anti-bacterial drugs for human caused evolving of the public health thread due to development of resistance by the bacteria towards the available anti­ bacterial agents. Benzothiazole which is a bicyclic ring system having sulphur and nitrogen in the ring have found to possess various pharmacological activities including anti-bacterial activity. Due to this idea, a series of 26 benzothiazole derivative compounds have been synthesized through the reaction between several substituted aldehyde and 2-aminothiophenol. The synthesized products were undergone thin layer chromatography and nuclear magnetic resonance to study their structures and to check their purity. Further study will be conducted in order to identify the anti-bacterial potential of the compounds.