Studies on the anti-inflammatory activities of kaempferia galanga extracts (rhizomes and leaves) in rats / Nor Faizura Ahmad Fuzlin

Kaempferia galanga, family Zingiberacae is commonly known as 'cekur' in Malay and is widely distributed throughout Malaysia and other Southeast Asian countries. The aim of the present study was to evaluate anti-inflammatory effect of ethyl acetate extract of Kaempferia galanga leaves and rhizomes using rats. Inflammation was induced by intraplantar (ip) administration of freshly prepared (0.1 ml) carrageenan in normal saline into the right paw of the rats. In this study, the optimum concentration of carrageenan induced edema was determined. The results showed that the optimal carrageenan concentration to induce edema was I%. Aspirin and corn oil were used as controls. Aspirin was used as a positive control as is a potent anti-inflammatory agent. The extract of Kaempferia galanga at all doses for both the rhizomes and leaves did not produce significant when the extract was given for treatment and for prophylaxis.