Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim

Mohd Yasim, Mohd Hadafi (2007) Effects of herbicide residues on reproduction and thyroid function / Mohd Hadafi Mohd Yasim. Degree thesis, Universiti Teknologi MARA (Kampus Puncak Alam).

Abstract

This study was carried out with a view to investigate the effects of residual doses of herbicide mixtures on endocrine and reproductive function in male SD rats. Animals were exposed to MRL, MTD and high doses from PND 23 to PND 53. Results show that increasing dose of herbicidal mixture of paraquat, 2,4-dichloridephenoxyacetic (2,4-D), glyphosate, and glufosinate delayed puberty in SD rats by 0.4 ± 0.1 (MRL), 1.0 ± 0.5 (MTD), and 4.4 ± 0.3 (high dose) days. These delays in sexual maturation were accompanied by significant changes in body weight, size of reproductive organs and non-reproductive organ and by alteration in natural hormone levels.

Metadata

Item Type:	Thesis (Degree)
Creators:	Creators Email / ID Num. Mohd Yasim, Mohd Hadafi UNSPECIFIED
Contributors:	Contribution Name Email / ID Num. Thesis advisor Iguegbe, Aloysius Umelo UNSPECIFIED
Subjects:	R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme:	Bachelor of Pharmacy
Keywords:	herbicide residues, reproduction, thyroid function
Date:	2007
URI:	https://ir.uitm.edu.my/id/eprint/99632