Evaluation of Malaysian herbs on artemia salina toxicity assay / Rozita Hanim Abdul Rahim

This study was conducted to identify the toxicity of Malaysian herbs towards the brine shrimp lethality assay. Eleven methanolic herbal extracts were evaluated with concentrations of 0.78, 1.56, 3.13, 6.25, 12.50, 25, 50, and 100 mg mL-1 against the brine shrimp lethality assay. The highest brine shrimp toxicity (IC50 = 0.02 mg mL-1) was observed in "Species 8". Meanwhile, "Species 4" has the lowest brine shrimp toxicity (IC50 = 30.40 mg mL-1) in this study. "Species 7" and "Species 9" did not exhibit lethality towards the brine shrimp for all concentration evaluated. From eleven methanolic herbal extracts that were evaluated, only nine methanolic herbal extracts exhibited toxicity towards the brine shrimp lethality assay with IC50 values ranging from 0.02 to 30.40 mg mL-1. There were "Species l ", "Species 2", "Species 3", "Species 4", "Species 5", "Species 6", "Species 8", "Species 10" and "Species 11" with IC50 values of 19.47 mg mL-1 , 16.20 mg mL-1, 11.14 mg mL-1, 30.40 mg mL-1, 8.02 mg m