Chemical constituents from the leaves of Mangifera indica / Sarina Binti Ahmad Wahid

Mangifera indica a species of Anacardiaceae or locally known as Mempelam, Pauh or
Mangga grows wild on lowland and few on the mountain. It is well known as a medicinal plant
and economic product commonly used by all race in many Asian countries. All parts of the
plant including the fruit, flower, leaves and stem are used in various ways to treat many health
ailments and diseases. Previous study indicated that flavonoids are the major chemical
constituents of Mangifera indica from the leaves part of the plant. In this work, the plant was
extracted with petroleum ether and methanol solvent. Isolation was conducted on the methanol
crude extract in order to obtain the pure compounds followed by structure elucidation of the
pure compound. The structure of pure compound was determined by spectroscopic methods
and also by comparing the experimental data with those from the literature. Phytochemical
investigation of the methanol extract of the leaf part of Mangifera Indica has afforded
compound X proposed to be 1, 3, 4-Trihydroxyl-1-(4-methoxy-phenyl)-3-(3, 4, 5 trihydroxyhydroxymethyl-
tetrahydro-pyran-2-yl)-butan-2-one. The structure of the flavanone was
established based on spectral studies using 1H-NMR, 13C-NMR, MS, UV and IR analysis.