Antimicrobial activity of Channa striatus extract againsts Staphylococcus aureus and Eschericia coli / Hairol Aswat Sabtu

Snakehead fish (Channa striatus) is an indigenous, predatory freshwater fish of Malaysia. It is a common food fish among the local populace with traditionally identified pharmacological benefits in treating wound and pain. A research was carried out to determine the inhibition effect of C. striatus extract on S. aureus and E. coli. This is essential in order to provide information for their effectiveness against bacteria causing wound infection. In this research, streptomycin was used as positive control while distilled water was used as negative control. Disc diffusion method was applied to observe the production of inhibition zone of S. aureus and E. coli on nutrient broth agar plate. There is a significance different effect between acidic mucus and acidic tissue extract for both fish. Therefore, this is the value to determine the comparative outcome of the results. The significance of this study were definitely provide an input on C. striatus extract through the antimicrobial properties that lead to the contribution to medical field. From experiment conducted founded that acidic tissue nor mucus extract of C. striatus did produce inhibition effects on the growth of gram positive bacteria S. aureus and negative bacteria E. coli on the nutrient broth agar plate through disc diffusion method. Statistical analysis showed that the antimicrobrial activity against E. coli was better than S. aureus in acidic tissue extract (3% acetic acid) and acidic mucus extract (3% acetic acid) of C. striatus due to P-value of 0.223 was more higher than S. aureus that has P-value of 0.152. When E. coli and S. aureus are intercept they are highly significance by the P-value of 0.00. The alternate hypothesis was accepted due to there was significance different.