Isolation and characterization of secondary metabolites from marine fungi / Durrah Fathiah Abdul Mutalib

Abdul Mutalib, Durrah Fathiah (2012) Isolation and characterization of secondary metabolites from marine fungi / Durrah Fathiah Abdul Mutalib. Degree thesis, Universiti Teknologi MARA (UiTM).

Abstract

The secondary metabolites of marine fungi were extensively studied since centuries ago. Some secondary bioactive metabolites showed interesting antibacterial properties. In this study, the sample of sea water was collected from Pantai Langkawi, Kedah, Malaysia. In order to identify the secondary metabolites of the marine fungi, the sample was inoculated on the PDA plate containing antibiotics and left to grow for several weeks. The fungi that to be cultured in the large scale was selected based on the colony form on the PDA containing antibiotics. It was then inoculated back on PDA and left to grow for
several weeks. The incubated fungus was then extracted and analyzed using HPLC and Semi-preparative HPLC. In addition, the fungal extraction was tested against E.coli, P.aeruginosa, E.faecium and S.aureus. This fungus is active against E.coli, S.aureus and E.faecium.

Metadata

Item Type: Thesis (Degree)
Creators:
Creators
Email / ID Num.
Abdul Mutalib, Durrah Fathiah
UNSPECIFIED
Contributors:
Contribution
Name
Email / ID Num.
Thesis advisor
Ali Shah, Syed Adnan
UNSPECIFIED
Subjects: Q Science > QR Microbiology > Microbial ecology > Water. Aquatic microbiology > Seawater. Marine microbiology
R Medicine > RM Therapeutics. Pharmacology > Drugs and their actions > Antibacterial agents
Divisions: Universiti Teknologi MARA, Shah Alam > Faculty of Pharmacy
Programme: Bachelor of Pharmacy (Hons.)
Keywords: Marine fungi; bioactive metabolites; antibacterial; Pantai Langkawi
Date: 2012
URI: https://ir.uitm.edu.my/id/eprint/65554
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