Synthesis, characterization and antimicrobial screening of schiff base ligand and copper(II) complexes / Nur Hafizah Adzis

Two copper(II) complexes derived from o-phenylenediamine and 4- methylbenzaldehyde or trans-cinnamaldehyde were synthesized. Structural features of Schiff base and complexes were determined by analytical and spectral techniques like elemental analysis, IR, UV - visible spectroscopy, melting point and molar conductivity measurements. The result suggested that the Schiff base ligands behaved as bidentate ligand coordinate through azomethine nitrogen to the central metal ions forming complex compound, ML1 while complex ML2 was prepared by using in-situ method. Molar conductance values in ethanol indicate both of complexes are non-electrolytic nature. The anti-microbial activity of the synthesized ligand and its complexes were studied against Escherichia coli and Staphylococcus aureus by disc diffusion method. The activity data shows that the metal complex (ML1) tends to be more potent against the microbial species, Escherichia coli than the parent Schiff base ligand (L1) and metal complex (ML2).