Enhancing drug delivery: advancements in hybrid aerogels and supercritical CO₂ drying

Supercritical fluid technology is a new approach in the pharmaceutical industry that uses supercritical fluids, mainly carbon dioxide (CO₂), to enhance drug delivery systems. These fluids exhibit unique properties of liquids and gases, making them ideal for aerogel production in drug delivery applications. Aerogels are open porous materials with large specific surface areas and high pore volume, making them attractive for drug carriers. They have been studied for their biodegradability and biocompatibility, making them promising carriers for drug delivery systems. Polysaccharides like cellulose, starch, and alginates are used to prepare organic aerogels, which are relatively inexpensive, highly biocompatible, and nontoxic.