Chitosan-pectin polymer film for transdermal drug delivery system

Mohd Aziz, Abdullah Aziim (2017) Chitosan-pectin polymer film for transdermal drug delivery system. [Student Project] (Unpublished)

Abstract

Chitosan and pectin are widely used in pharmaceutical products due to their excellent characteristics such as mucoadhesive, controlled release property, as well as skin permeation enhancing effect. In this study, three types of transdermal films namely chitosan, pectin and chitosan-pectin composite were prepared using acetaminophen as the model drug and their drug permeation profiles were investigated. It was found that both chitosan and pectin film showed higher average drug permeation of 6.0994±1.1063% and 5.7378±1.7608% respectively when compared to chitosan pectin film where the average drug permeation was only 0.8535±0.4811 % after 24 hours. In conclusion, both chitosan and pectin are potentially suitable for controlled transdermal delivery of acetaminophen while the chitosan-pectin composite might be useful for topical drug delivery.

Metadata

Item Type:	Student Project
Creators:	Creators Email / ID Num. Mohd Aziz, Abdullah Aziim UNSPECIFIED
Contributors:	Contribution Name Email / ID Num. Thesis advisor Anuar, Nor Khaizan UNSPECIFIED
Subjects:	R Medicine > RM Therapeutics. Pharmacology > Drugs prescribing R Medicine > RM Therapeutics. Pharmacology > Drugs and their actions
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme:	Bachelor of Pharmacy
Keywords:	Chitosan-pectin polymer film, Transdermal drug
Date:	2017
URI:	https://ir.uitm.edu.my/id/eprint/124589