Wound healing property of hibiscus rosa sinensis-pectin hydrogel

The potential of Hibiscus rosa-sinensis (HRS)-pectin hydrogels as a wound dressing for partial thickness thermal burn wounds was investigated. The experiment was conducted using male Sprague Dawley rats, which were divided into three groups with different types of treatment; group A (gauze), group B (pectin hydro gel) and group C (HRS-pectin hydrogel). The wound healing property was assessed by percentage of wound closure, wound images and histology assessment. The results showed that the HRS-pectin hydrogels can promote the healing process of partial thickness thermal burn wound in rats within 21 days. Histological study showed that group treated with HRS-pectin hydrogel promoted excellent collagen deposition and complete re-epithelization when compared to control and rats treated with pectin hydrogel, thus confirming its potential as a wound dressing in promoting partial thickness wound healing.