Microbial transformation of ethinyl estradiol

Mohd Narzuki, Amira Syakirin (2017) Microbial transformation of ethinyl estradiol. [Student Project] (Unpublished)

Abstract

The studies on microbial transformation have been well established as an important tool for the modifications of highly complex structure like steroids. Primarily, it can be used to synthesize chemical structure that might be difficult to obtain synthetically. Currently, research has been focused on structural modifications of bioactive steroids by using various microorganisms in order to obtain biologically potent compound with diverse structure. In this study, a steroid compound which is an ethinyl estradiol has been used as a substrate and undergo biotransformation with two selected endophytes. High Performance Liquid Chromatography (HPLC) has been performed m order to identify the biotransformed products.

Metadata

Item Type:	Student Project
Creators:	Creators Email / ID Num. Mohd Narzuki, Amira Syakirin UNSPECIFIED
Contributors:	Contribution Name Email / ID Num. Thesis advisor Sultan, Sadia UNSPECIFIED
Subjects:	Q Science > QR Microbiology > Microbial ecology R Medicine > RS Pharmacy and materia medica > Materia medica > Pharmaceutical chemistry
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme:	Bachelor of Pharmacy
Keywords:	Microbial, Ethinyl estradiol, High performance liquid chromatography (HPLC)
Date:	2017
URI:	https://ir.uitm.edu.my/id/eprint/123255