Abstract
The aim of this study is to formulate three different oil in water emulsion cream loaded with IMEXGEL® and natural oil which were jojoba oil, virgin coconut oil (VCO) and olive oil. About 39 formulation in total have been introduced by Design Expert 10 (DX- 10) software for three different natural oil creams. In other words 13 formulation with different concentration of natural oil and IMEXGEL® 305 have been suggested for each natural oil creams. The physical characterisation study have been done to these creams to determine and compare their droplet size distribution, rheology and texture. Texture analysis generated 4 parameters which were firmness, consistency, cohesiveness and index of viscosity. Texture is the main attributes to attract the consumer acceptation toward the cosmetic product. Besides, all the responses result from the physical characterization study were analysed with Response Surface Method (RSM) by Design Expert 10 (DXI 0). Result from this study showed that cream prepared by using commercial emulsifier IMEXGEL® were able to produced good physical characteristics of the creams but it depends on the concentration of both IMEXGEL® and natural oils. Based on physical characterization analysis, mean droplet size, uniformity and value of tan 8 showed different pattern in three dimension of response surface plot on different natural oil creams. However, firmness, cohesiveness, index of viscosity, storage modulus, loss modulus and complex viscosity showed similar pattern on three dimension on response surface method on the jojoba oil cream, VCO cream and olive oil cream. Evaluation of the stability on the creams by using LUMiFuge® stability analyzer have shown no separation of the creams during simulation of storage for 6 month at room temperature (±25°C) and conclude that all the creams were stable.
Metadata
| Item Type: | Student Project |
|---|---|
| Creators: | Creators Email / ID Num. Mosen, Fatin Nure'zzati UNSPECIFIED |
| Contributors: | Contribution Name Email / ID Num. Thesis advisor Bustami Effendi, Tommy Julianto UNSPECIFIED |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology > Drugs and their actions > Aromatic plants. Aromatherapy. Including essences and essential oils |
| Divisions: | Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy |
| Programme: | Bachelor of Pharmacy |
| Keywords: | Natural oil creams, IMEXGEL®, Cold mixing technique |
| Date: | 2016 |
| URI: | https://ir.uitm.edu.my/id/eprint/120930 |
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