Influence of aquilaria subintegra leaf particle size on reaction of pancreatic lipase and cooking oil

Cooking oil extensively used & consumed in Malaysian cuisines, leads to high obesity rates in Malaysia. This cooking oil is hydrolysed inside the human digestive system by the enzyme pancreatic lipase. It is known from various researches & experiments over the years that the inhibition of this pancreatic lipase’s enzyme activity slows down the hydrolysis of cooking oil, thereby reducing intake of cooking oils and fats into the human body and slowing down the accumulation of fats. It is known that a few plants contain chemical extracts that in turn contains inhibitors of pancreatic lipase activity, and the leaf extracts of the agarwood plant species Aquilaria Subintegra are suspected to hold such inhibitory activity. The experiment is then done to investigate the influence of the particle size of A. Subintegra leaf extracts on the hydrolytic reaction of pancreatic lipase on cooking oil. From the experiments, it is shown that there is a slight downward trend of pancreatic lipase activity with increased A. Subintegra leaf extract concentration as a surrogate for decreased leaf particle size, however more rigorous testing is required to obtain definitive results.