Ecobiocream: exploring the antimicrobial synergism between gelenggang leaves and red dragon fruit peel extracts in a novel antiseptic cream

This study focuses on developing a sustainable antiseptic cream by combining extracts from gelenggang leaves and red dragon fruit peel. The cream offers an alternative therapy to address the high cost of conventional drugs in developing countries and the rising issue of antimicrobial resistance, particularly against microorganisms like methicillin-resistant Staphylococcus aureus (MRSA). Gelenggang leaves, traditionally used for skin ailments, and red dragon fruit peel, a commonly discarded waste rich in bioactive compounds, are repurposed to create an eco-friendly, plant-based solution. Antimicrobial susceptibility testing revealed significant activity against Gram-positive bacteria and fungi, including MRSA and Candida albicans, though it showed limited efficacy against Gram-negative bacteria. This highlights the potential of plant extracts in combating antimicrobial resistance. The cream is practical, suitable for all skin types, and integrates effortlessly into daily skincare routines. Its reliance on repurposed fruit waste supports the United Nations Sustainable Development Goals (SDGs) by reducing environmental impact and promoting waste reduction. Beyond antiseptic properties, the cream offers multifunctional benefits such as wound healing and anti-inflammatory effects. By presenting a safe, natural alternative to conventional antiseptics, the cream exemplifies innovative skincare that tackles health and environmental challenges while promoting responsible consumption and sustainability.