Induction of secondary metabolites through co-culturing of fungi species

Natural products and their derivatives such as the secondary metabolites have been sources of several therapeutic agents which play an important role in drug discovery for a long time. In the pharmaceutical field, secondary metabolites and biochemical indicators have develop interest to mankind due to their pharmacological and toxic properties. In the production of secondary metabolites, the interaction between fungi is important. The induction of new secondary metabolites in GS4 l+CR15 .2, GS4 l+CR25, GS41+CM01, GS41+GS47 and GS38+GM29. GS41. In this experiment, GS41 showed a tremendously result by inducing new secondary metabolites. Through this experiment, some peaks of the fungi species were altered when they were co-cultured. This was done by analysing the data through UHPLC analysis. The type of interaction between fungi and other microorganism is defined as 'co-culture'.