Pore characterization of porous Poly-Ɛ-aprolactone/Hydroxyapatite nano composite analyse by software Image J: article

Supercritical CO₂ gas foaming method has been one of the favorable method in producing polymer composite for Bone Tissue Engineering due to absent of inorganic solvent that will might cause inflammation if in contact with cell tissue. Besides, it also gives the ability to control the process to obtain various pore size and porosity. This is the method to produce PCL/HA composites which is been recognize for its biocompatibility and mechanical structure. Several parameters of process such as foaming temperature and pressure will affect the pore characteristics alongside with the HA content. In this study, the effect of temperature, pressure and HA content will be investigated on the pore characteristic such as porosity, pore size, distribution and density. The samples were fabricated at 10MPa, 20MPa and 30MPa at 40°C and 45°C with 10%, 20% and 30% HA content. The characteristic are analyzed using Software Image J. Results show that increase in temperature and pressure cause the pore size, porosity and density to increase. Overall, the pores size obtained are in compliance with the requirement to be used in Bone Tissue Engineering.