Abstract
Skin agmg is a complex biological process, which occurs when there is an appearance of a wrinkle on the skin and the reduction of skin elasticity. Intrinsic and extrinsic factors contribute to the aging activity. Intrinsic aging process includes the loss of skin elasticity and collagen while extrinsic aging process affects the dermis where there is a degradation of collagen and elastic fibres due to the exposure of solar radiation or UV. There are a lot of cosmetic products claiming to have anti-aging effect but the cost is expensive. The product formulation needs to aim penetration of active ingredients to the dermal area where collagen and elastic fibre are being produced. The extract of Hibiscus sabdariffa L. has a potential in contributing to anti-aging activity by its chemical constituent such as anthocyanins, flavonoids and ascorbic acid. It is also a less costly ingredient as it can be obtained locally. Three cream formulations containing different concentrations of extract were produced. The physical characterisation studies were performed. These include stability of the freshly prepared aqueous cream, pH, texture and particle size. These were compared with a commercial formulation. In order to evaluate the effectiveness of anti-aging activity of the extract, skin elasticity was measured using Cutometer Dual MPA580 and VisioscanVC98. All results were analysed statistically using SPSS to see the significance difference. From the results obtained, Formulation B which consists of 2%w/w Hibiscus sabdariffaL. Extract showed reduced wrinkle appearance and an increase in skin elasticity.
Metadata
Item Type: | Student Project |
---|---|
Creators: | Creators Email / ID Num. Hussain, Nur Ain Hidayah UNSPECIFIED |
Contributors: | Contribution Name Email / ID Num. Thesis advisor Sahudin, Shariza UNSPECIFIED |
Subjects: | Q Science > QD Chemistry > Organic chemistry Q Science > QK Botany > Plant physiology > Botanical chemistry. Phytochemicals |
Divisions: | Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy |
Programme: | Bachelor of Pharmacy |
Keywords: | Anti-aging, Aqueous cream, Hibiscus sabdariffa l. |
Date: | 2015 |
URI: | https://ir.uitm.edu.my/id/eprint/118601 |
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