The potential of Garcinia Mangostana pericarp as anti-fungi cream

Garcinia mangostana pericarp contains xanthones as the active component that can be used to treat fungi due to its anti-fungi activities. In this experiment, G. mangostana is being used to treat Candida albicans that can cause candidiasis on human due to its overgrown on parts of human body. Though there are treatments such as cream that has been commercialized, the cream may cause severe liver injury due to the content of steroids. The aim of this study is to assess the potential of G. mangostana pericarp as antifungi agent, to formulate anti-fungi cream enhanced with G. mangostana pericarp and to compare the G. mangostana cream with synthetic drugs that has been marketed. The extract was prepared using ethanol solvent extraction method. The variable was tested on C. albicans at different mass of G. mangostana powder, the temperature of drying and the duration of extraction. Zaricort cream is being used as the controlled experiment. All of it shows a positive result on the inhibition of C. albicans. The finding shows that the best inhibition of the C. albicans is at 1.25 gram of Garcinia mangostana powder with the diameter inhibition of C.albicans of 1.35 ± 0.25 cm. The revelation of this preliminary study has a prominent potential to act as anti-fungi on C. albicans and ultimately become an alternative to substitute existing commercialized medicine.