Evaluation of fungal culture media for the production of secondary metabolites by aquatic fungi / Mardhiah Muhsin

Marine fungi are one of the sources that produced a lot of secondary metabolites. Secondary metabolites have been proved in many studies used as developing of a new drug from the lead compound activity. Some secondary metabolites showed as anticancer, antibacterial, antihelminthic and many more. In this study, two types of marine fungi were inoculated and growth in different media conditions which are PDA, PDB and MEA. The incubated fungi was then being extracted and analysed for their production of secondary metabolites using TLC and HPLC methods. Fungus 2 showed more production of secondary metabolites in the PDA and PDB compared with Fungus l based on the elution compound on TLC and also the HPLC chromatogram. However, both fungi are favourable growth in PDA and PDB because of more compounds seen on TLC plates from the spot of PDA and PDB fungal cultures and also more peaks formed in HPLC chromatogram of PDA and PDB fungal cultures.