Development of PCR based method for the detection of genetic polymorphism of leptin receptor (LEPR) / Nurul Anis Syuhada Zulkifle

Zulkifle, Nurul Anis Syuhada (2014) Development of PCR based method for the detection of genetic polymorphism of leptin receptor (LEPR) / Nurul Anis Syuhada Zulkifle. Degree thesis, Universiti Teknologi MARA (Kampus Puncak Alam).

Abstract

The problem of overweight and obesity among populations in Asia have been highlighted for more than a decade. As a result, many chronic diseases increase steadily with increasing body mass index (BMI). Overweight and obesity lead to various problematic metabolic effects on blood pressure, cholesterol, triglycerides and insulin resistance. Even though there are many aetiologic factors causing obesity, obesity had been associated with genetic polymorphism leptin receptor gene. Leptin acts through its receptor, leptin receptor (LEPR) which is a single transmembrane-domain receptor of the cytokine-receptor family. In this study, Polymerase Chain Reaction (PCR) based method was done to detect the presence of LEPR polymorphism.

Metadata

Item Type:	Thesis (Degree)
Creators:	Creators Email / ID Num. Zulkifle, Nurul Anis Syuhada UNSPECIFIED
Contributors:	Contribution Name Email / ID Num. Thesis advisor Teh, Lay Kek UNSPECIFIED
Subjects:	R Medicine > RC Internal Medicine > Specialties of internal medicine > Metabolic diseases > Obesity
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme:	Bachelor of Pharmacy
Keywords:	PCR based, genetic, leptin receptor (LEPR)
Date:	2014
URI:	https://ir.uitm.edu.my/id/eprint/111228