Effect of polyethylene glycol (PEG) length on the fluorescence intensity of carbon dots / Muhamad Azwan Hammad Ahmad

Hammad Ahmad, Muhamad Azwan (2014) Effect of polyethylene glycol (PEG) length on the fluorescence intensity of carbon dots / Muhamad Azwan Hammad Ahmad. Degree thesis, Universiti Teknologi MARA (Kampus Puncak Alam).

Abstract

Carbon dots (CD) are luminescent nanoparticles that can be used to track biological processes inside cells. They are less toxic than similar alternatives, making them more suitable for use in live biological systems, but the light-emitting properties of those currently made are not ideal. CD is one of the recent substance that are being used as a tools for bio-imaging probes. Fluorescent CD-based imaging probes have becoming a new medical diagnostic tools due to its advance labelling technology. One of its characteristics is superior brightness and photo­ stability. Besides that, the usage of carbon nanoparticles is safe as it is non-toxic which is suitable for biological staining and diagnostics. In this research, the factors affecting fluorescence intensity of CD was investigated by treating the CD by via surface passivation method. The objective of this study is to find an optimum amount of surface passivating agent i.e. polyethylene glycol (PEG) required to produce maximum fluorescence spectra. It has been concluded that as the length of PEG used in the passivation method increases, the fluorescence intensity of CD was enhanced.

Metadata

Item Type: Thesis (Degree)
Creators:
Creators
Email / ID Num.
Hammad Ahmad, Muhamad Azwan
2011649752
Contributors:
Contribution
Name
Email / ID Num.
Thesis advisor
Mohd Suhaimi, Azyyati
UNSPECIFIED
Subjects: R Medicine > RS Pharmacy and materia medica > Pharmacopoeias
Divisions: Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme: Bachelor of Pharmacy
Keywords: polyethylene glycol (PEG), fluorescence intensity, carbon dots
Date: 2014
URI: https://ir.uitm.edu.my/id/eprint/111084
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