Malaysian traditional herbs: inhibition of traditional herbs on CYP2D6 enzyme / Raihan Muhamedin

Muhamedin, Raihan (2009) Malaysian traditional herbs: inhibition of traditional herbs on CYP2D6 enzyme / Raihan Muhamedin. Degree thesis, Universiti Teknologi MARA (Kampus Puncak Alam).

Abstract

Herbal medicines usually had been taken concomitantly with the conventional drugs. The metabolism of both of them might be in the same cytochrome P450; CYP2D6. The purpose of this study was to investigate the effect of these herbs on the CYP2D6 enzyme using fluorogenic kits; Vivid® CYP2D6 Screening Kits (USA). The results obtained were all of the herbs tested showed positive inhibition except for the herbs; Pinang, Selasih, Senduduk, Serai Wangi, Tenggek Burung, Terung Pipit, Tongkat Ali and Mas Cotek. These results indicate that many Malaysian traditional herbs extracts had an inhibitory effect on CYP2D6.

Metadata

Item Type:	Thesis (Degree)
Creators:	Creators Email / ID Num. Muhamedin, Raihan UNSPECIFIED
Contributors:	Contribution Name Email / ID Num. Thesis advisor Choo, Chee Yan UNSPECIFIED
Subjects:	H Social Sciences > HD Industries. Land use. Labor > Special industries and trades > Pharmaceutical industry R Medicine > RS Pharmacy and materia medica > Materia medica > Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme:	Bachelor of Pharmacy
Keywords:	Malaysian traditional herbs, CYP2D6 enzyme
Date:	2009
URI:	https://ir.uitm.edu.my/id/eprint/106677