CellTrix Pro: bioengineered scaffold kit for successful MSC differentiation / Nur Sufiah Zulkifli ... [et al.]

Zulkifli, Nur Sufiah and Ab-Rahim, Sharaniza and Koh, Ching Theng and Muhamad, Mudiana (2024) CellTrix Pro: bioengineered scaffold kit for successful MSC differentiation / Nur Sufiah Zulkifli ... [et al.]. In: UNSPECIFIED.

Abstract

The CellTrix Pro kit is an innovative biomaterial scaffold designed to facilitate the differentiation of mesenchymal stem cells (MSCs). This kit aims to address key challenges in tissue engineering and regenerative medicine by providing a scaffold that closely mimics the natural extracellular matrix that meet the structural and biological parameters, thus creating an ideal environment for MSCs growth and differentiation. The CellTrix Pro kit features a three-dimensional scaffold made from biocompatible and biodegradable materials, included with optimized cocktails of growth factors and growth media. These components are tailored to support MSCs differentiation to osteogenic, chondrogenic, and adipogenic. The porosity microarchitecture of the scaffold enhances cell viability, proliferation, and differentiation efficiency. In vitro studies demonstrated the kit’s superior performance, showing a significant improvement in the speed and reliability of MSCs differentiation compared to conventional methods making it more efficient and reproducible for MSCs differentiation. The CellTrix Pro kit accelerates the production of high-quality, specialized cells suitable for various therapeutic applications with a straightforward and easy-to-follow protocol, ensuring that researchers can consistently achieve high- quality results. With broad applications in tissue repair, and disease modeling, CellTrix Pro kit offers a promising solution for treating degenerative diseases and injuries. It provides researchers with a powerful tool to advance stem cell biology and develop new therapeutic strategies. In conclusion, the CellTrix Pro kit represents a significant advancement in MSCs differentiation technology, with the potential to revolutionize regenerative medicine and improve patient outcomes.

Metadata

Item Type: Conference or Workshop Item (Paper)
Creators:
Creators
Email / ID Num.
Zulkifli, Nur Sufiah
UNSPECIFIED
Ab-Rahim, Sharaniza
UNSPECIFIED
Koh, Ching Theng
UNSPECIFIED
Muhamad, Mudiana
UNSPECIFIED
Contributors:
Contribution
Name
Email / ID Num.
Chief Editor
Abdul Rahman, Zarinatun Ilyani
UNSPECIFIED
Editor
Mohd Nasir, Nur Fatima Wahida
UNSPECIFIED
Editor
Kamarudin, Syaza
UNSPECIFIED
Designer
Ramlie, Mohd Khairulnizam
UNSPECIFIED
Subjects: T Technology > T Technology (General) > Technological change > Technological innovations
Divisions: Universiti Teknologi MARA, Perak > Seri Iskandar Campus > Faculty of Architecture, Planning and Surveying
Journal or Publication Title: 13th International Innovation, Invention & Design Competition (INDES 2024)
Page Range: pp. 238-240
Keywords: scaffold, MSC differentiation, tissue engineering, regenerative medicine, extracellular matrix
Date: 2024
URI: https://ir.uitm.edu.my/id/eprint/106576
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