The effects of diabetes on female sex hormone levels / Nur Shahirul Saidin

Saidin, Nur Shahirul (2009) The effects of diabetes on female sex hormone levels / Nur Shahirul Saidin. Degree thesis, Universiti Teknologi MARA (Kampus Puncak Alam).

Abstract

We analyzed the effects of streptozotocin-induced diabetes on the female hormone level in Wister Kyoto (WKY) rats. There was reduced sensitive of estradiol and progesterone in diabetes mellitus compared to levels in normal tissue and serum. Both hormones were slightly lower in female diabetic rats compared to non diabetic rats. Diabetes may disrupt steroidogenesis or alter the Hypothalamus-Pituitary-Gonadal (HPG) axis function. Estradiol was lower compared to progesterone in diabetic aorta probably due to diabetes induced loss of estrogenic signaling m female WKY rats.

Metadata

Item Type:	Thesis (Degree)
Creators:	Creators Email / ID Num. Saidin, Nur Shahirul UNSPECIFIED
Contributors:	Contribution Name Email / ID Num. UNSPECIFIED lguegbe, Aloysius Umelo UNSPECIFIED
Subjects:	H Social Sciences > HD Industries. Land use. Labor > Special industries and trades > Pharmaceutical industry
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme:	Bachelor of Pharmacy
Keywords:	diabetes, female sex hormone
Date:	2009
URI:	https://ir.uitm.edu.my/id/eprint/105854