Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid

Che Hamid, Norazura (2009) Investigation on contact angle during hydrotropic solubilization of the drug ketoconazole and griseofulvin / Norazura Che Hamid. Degree thesis, Universiti Teknologi MARA (Kampus Puncak Alam).

Abstract

The aqueous solubility of drug is often a limiting factor while developing the most desirable dosage form. Among the several techniques of solubility enhancement, hydrotropic solubilization is considered as one of the safest method. Many work highlighted the effect of solubility enhancers in improving solubility of the drug, but no detailed explanation about the molecular processes during the improving phenomenon. The present study deals with experiments so to highlight solute solvent interaction and related modifications in case of the presence of hydrotropic agents. Contact angle was carried out in order to obtain valuable information regarding the solute solvent interactions.

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Item Type: Thesis (Degree)
Creators:
Creators
Email / ID Num.
Che Hamid, Norazura
UNSPECIFIED
Contributors:
Contribution
Name
Email / ID Num.
Thesis advisor
Tripathy, Minaketan
UNSPECIFIED
Subjects: R Medicine > RS Pharmacy and materia medica > Pharmacopoeias
R Medicine > RS Pharmacy and materia medica > Materia medica > Pharmaceutical dosage forms
R Medicine > RS Pharmacy and materia medica > Materia medica > Pharmaceutical supplies
Divisions: Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy
Programme: Bachelor of Pharmacy
Keywords: Ihydrotropic solubilization, drug, ketoconazole, griseofulvin
Date: 2009
URI: https://ir.uitm.edu.my/id/eprint/105206
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