Chemical constituents from the leaves of Mangifera indica / Sarina Ahmad Wahid

Mangifera indica a species of Anacardiaceae or locally known as Mempelam, Pauh or Mangga grows wild on lowland and few on the mountain. It is well known as a medicinal plant and economic product commonly used by all race in many Asian countries. All parts of the plant including the fruit, flower, leaves and stem are used in various ways to treat many health ailments and diseases. Previous study indicated that flavonoids are the major chemical constituents of Mangifera indica from the leaves part of the plant. In this work, the plant was extracted with petroleum ether and methanol solvent. Isolation was conducted on the methanol crude extract in order to obtain the pure compounds followed by structure elucidation of the pure compound. The structure of pure compound was determined by spectroscopic methods and also by comparing the experimental data with those from the literature. Phytochemical investigation of the methanol extract of the leaf part of Mangifera Indica has afforded compound X proposed to be 1, 3, 4-Trihydroxyl-1-(4-methoxy-phenyl)-3-(3, 4, 5 trihydroxyhydroxymethyl-tetrahydro-pyran-2-yl)-butan-2-one. The structure of the flavanone was established based on spectral studies using 1H-NMR, 13C-NMR, MS, UV and IR analysis.