Prevalence of dengue virus by using rapid immunochromatographic test method in PPUKM from Jan 2015 to March 2015 / Nur Ain Kamaruzzaman

Dengue virus (DENV) infection is one of the major global public health problems. It is caused by the four DENV serotypes that are transmitted by Aedes mosquitoes. The infection usually occurs with clinical manifestations ranging from an asymptomatic or mild febrile illness as dengue fever to the potentially life-threatening illness, dengue hemorrhagic fever and dengue shock syndrome. The aims of this study were to compare the frequency of patients infected by DENV based on gender, races and age groups. This study is conducted from January 2015 until March 2015 among patients who were diagnosed at Pusat Perubatan Universiti Kebangsaan Malaysia. Serum samples were collected and DENV specific IgM and IgG antibodies were determined by using immunochromatographic test. Out of 223 samples shown in Table 4.1.1, 52.5% samples were positive to male patients while 47.5% were positive to female. The highest number of positive result based on the races was Malay communities that is 58.0% and the lowest result was Indian ethnics that is 6.1% only got DENV infection. 62 cases is positive to primary, IgM, response among the antibodies. The prevalence of age group showed that out of 400 samples, young adult gave highest result compare the other age group. Dengue is highly serious disease in the population in Malaysia and might be endemic for a long time in Malaysia. Public awareness, proper vector control and strengthening surveilllance must to get a serious attention to government and public people to keep the infection rates decrease.