Abstract
Skin serves as protective barrier against external insults to the human body, including mechanical and environmental stressors, and the entry of foreign chemical and microbe. Maintaining the epidermal barrier is essential for normal regulation of skin function. Skin surface is directly exposed to hostile environments that can induce changes in skin function. Both virgin coconut oil (VCO) and tocotrienols (TCTs) exhibit antioxidant properties that are beneficial in promoting the good appearances of skin. The present study was conducted to investigate the efficacy of topical application ofVCO enriched TCTs in improving skin parameters. 30 healthy students (18 females and 12 males), aged 22 ± 2 years were recruited for this study. Subjects were randomly divided to three treatment groups (group 1 = VCO enriched TCTs, group 2 = VCO, group 3 = control). Moisture content, as well as other skin surface structure and skin elasticity were determined for group 1 (VCO enriched TCTs) and group 2 (VCO) versus untreated control group. Statistical evaluation according to independent sample t-test indicates a greater efficacy for VCO enriched TCTs. Skin surface parameter showed an improvement but did not show significant changes. VCO enriched TCTs showed a significant improvement of skin elasticity for gross elasticity and skin fatigue parameters. All subjects were satisfied with the treatment and gave positive feedback for self-assessment. It can be concluded that VCO enriched TCTs was more effective in improving skin conditions. None of the participating test subjects had any side effects throughout the study.
Metadata
Item Type: | Thesis (Degree) |
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Creators: | Creators Email / ID Num. Ab. Rahman, Norazida UNSPECIFIED |
Contributors: | Contribution Name Email / ID Num. Thesis advisor Bustami Effendi, Tommy Julianto UNSPECIFIED |
Subjects: | R Medicine > RS Pharmacy and materia medica > Materia medica > Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic) |
Divisions: | Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Pharmacy |
Programme: | Bachelor of Pharmacy |
Keywords: | virgin coconut oil, tocotrienols, skin |
Date: | 2008 |
URI: | https://ir.uitm.edu.my/id/eprint/103990 |
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