Antimicrobial activity of different fungal extracts (NWlla, NWlb, 11L1c) / Nasyrah Amalina Sarginan

The increasing number of newly emerging pathogens, uncontrolled multi drug resistance towards stains and widely spreading infectious disease acquired a new antimicrobial agent to be discovered and developed immediately. The aims of this study is to find out either the isolated fungi used in this study have antimicrobial activity or not besides studying the morphology of the fungi and do extraction process to yield the crude extract. The method used is by cultivating the fungi on the Malt extract agar and Malt extract broth for 14 days and then do extraction process using EtOAc and n-BuOH. The antimicrobial activity of the fungi is tested using Disk Diffusion Method. From the findings, none of the isolated fungi shows antimicrobial activity. This negative result might be due to several factors such as too low extract concentration used and the metabolite of the fungi may be destroyed during the extraction process.