Cytological and molecular analysis of anti-tumour bioactivities of Urginea maritima (L.) baker aqueous extract on human malignant neuroblastoma with its neuroprotection ability / Maati Musbah Saleh Elghuol

Saleh Elghuol, Maati Musbah (2016) Cytological and molecular analysis of anti-tumour bioactivities of Urginea maritima (L.) baker aqueous extract on human malignant neuroblastoma with its neuroprotection ability / Maati Musbah Saleh Elghuol. PhD thesis, Universiti Teknologi MARA (UiTM).
Abstract

This study was conducted with the hypothesis that the phytochemical closely related to Libyan medicinal herb, Urginea maritima (L.) Baker constituents within waterbased extract would own appropriately powerful properties that contribute to intrinsic regulation specific antitumour activities in human malignant SH-SY5Y neuroblastoma cells. The purpose of the present study was to explore the characterisation and identification of the major phytochemical of the U. maritima aqueous extract. Additionally, the study also aimed to evaluate their effectiveness on the cellular and molecular mechanism associated with the main anti-tumour criteria.

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