Comparative reproductive assessment of male mice, mus musculus following consumption of ethanolic extract of averrhoa bilimbi, cosmos caudatus and pereskia bleo / Marysia Julius Booh

Averrhoa bilimbi, Cosmos caudatus and Pereskia bleo are among the local herbs found in Malaysia. These plants are frequently consumed due to the belief that they are able to strengthen and boost up general health, besides prevalently used in traditional medication. The present study assessed the reproductive potential of male ICR mice treated with ethanolic extract of A. bilimbi, C. caudatus and P. bleo plants, following the Organization for Economic Co-operation and Development (OECD) Guidelines 407 and 421. The evaluation involved 4 dosages of 50, 125, 500 and 1000 mg/kg b.wt of each plant, with 5 male mice per treatment. Meanwhile, mating analysis involved groups that gave higher and lower sperm quality only, where each of the treated male mice from the selected groups were mated with 3 female mice. The control group received saline.