Antimicrobial potential of medicinal plant extract towards multi drug resistant microbial strain / Norazlina Ahmad, Choo Chee Yan and Zaidatul Azmi Abd Rahman

Ahmad, Norazlina and Choo, Chee Yan and Abd Rahman, Zaidatul Azmi (2006) Antimicrobial potential of medicinal plant extract towards multi drug resistant microbial strain / Norazlina Ahmad, Choo Chee Yan and Zaidatul Azmi Abd Rahman. [Research Reports] (Submitted)

Abstract

Aim: Some traditional Malay medicinal plants were selected and evaluated for the antimicrobial activity potential against sensitive strains of Staphylococcus aureus and Eschericia coli and multidrug resistant strains of methicillin resistant Staphylococcus aureus (MRSA) and extended spectrum beta lactamase E.coli (RESCO). Method: The ground dried leaves or seeds were extracted with 70 % aqueous methanolic solution for two days. The solution was subsequently filtered and dried in vacuo using a rotary evaoparator. The dried methanolic extract was later dissolved in 2 % DMSO and subjected to antimicrobial evaluation by means of micro well plate dilution method. Conclusion: All the traditional Malay medicinal plants inhibited the growth of Staphylococcus aureus strains with inhibition index between 0.36 and 0.84. The leaves of Cassia alata and seeds of Cassia surattensis exhibited moderate activity against both the MRSA and ESBL E.coli strains. All the Lycopodium species evaluated inhibited the
growth of Staphylococcus aureus strain with inhibition index ranging from 0.61 to 1.10. Three of the Lycopodium species inhibited the growth of the MRSA strain.

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Item Type: Research Reports
Creators:
Creators
Email / ID Num.
Ahmad, Norazlina
UNSPECIFIED
Choo, Chee Yan
UNSPECIFIED
Abd Rahman, Zaidatul Azmi
UNSPECIFIED
Subjects: Q Science > QR Microbiology > Microbial ecology
Divisions: Universiti Teknologi MARA, Shah Alam > Research Management Centre (RMC) > Institute of Research, Development and Commercialization (IRDC)
Date: 2006
URI: https://ir.uitm.edu.my/id/eprint/7745
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