Fructus mume aqueous extract's antibacterial effect on multispecies biofilm / Afzan Adilah Ayoub, Gary Shun-Pan Cheung

Ayoub, Afzan Adilah and Cheung, Gary Shun-Pan (2022) Fructus mume aqueous extract's antibacterial effect on multispecies biofilm / Afzan Adilah Ayoub, Gary Shun-Pan Cheung. Compendium of Oral Science (CORALS), 9 (1). pp. 1-12. ISSN 2489-1102; 2637-0611


Aim: The purpose of this study was to determine the efficacy of several irrigants and an aqueous extract of Fructus mume in eradicating three kinds of biofilm. Materials and Methods: A three-species biofilm of E. faecalis, P.gingivalis and F.Nucleatum were cultivated for one week on Thermanox™ plates. Each specimen was immersed for 8 minutes in various irrigants: Fructus mume solution, buffered citric acid, sodium hypochlorite and control (non-irrigated). LIVE/DEAD® BacLightTM staining and confocal light scanning microscopy were used to determine the number of viable bacteria left on the substrate. The same biofilm was then extracted and subjected to scanning electron microscopy (SEM). Results: Images were taken at 12 locations across the biofilm, which were then classified into four areas of concern: Bottom, which would spend the most of the experiment submerged in the solution; It was struck in the centre by the stream of irrigant.; Middle and Upper, where the impression was caused by the irrigant splattering or vaporizing. Results of the amount of viable bacteria residual indicated that Fructus mume showed no significant activity, with an effect like control and even buffered citric acid, and significantly inferior to sodium hypochlorite. Conclusion: Sodium hypochlorite (0.5%) solution was greater to buffered citric acid, Fructus mume and control group as an antimicrobial agent against three-species biofilm.


Item Type: Article
Email / ID Num.
Ayoub, Afzan Adilah
Cheung, Gary Shun-Pan
Subjects: R Medicine > RK Dentistry > Oral and dental medicine. Pathology. Diseases
R Medicine > RM Therapeutics. Pharmacology > Drugs and their actions > Antibacterial agents
Divisions: Universiti Teknologi MARA, Selangor > Sungai Buloh Campus > Faculty of Dentistry
Journal or Publication Title: Compendium of Oral Science (CORALS)
UiTM Journal Collections: UiTM Journal > Compendium of Oral Science (CORALS)
ISSN: 2489-1102; 2637-0611
Volume: 9
Number: 1
Page Range: pp. 1-12
Keywords: E.faecalis,P.gingivalis , F.nucleatum fructus mume, dental irrigants, biofilm, traditional Chinese medicine, Japanese prune.
Date: 2022
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