Comparison of antimicrobial activity between Phyllanthus acidus water extract and commercial mouthwash on oral microbe / Muhammad Shafiq Rosli

Rosli, Muhammad Shafiq (2012) Comparison of antimicrobial activity between Phyllanthus acidus water extract and commercial mouthwash on oral microbe / Muhammad Shafiq Rosli. Degree thesis, Universiti Teknologi MARA (UiTM).

Abstract

Phyllanthus acidus is a common village tree, especially found in northern region of peninsular Malaysia. Phyllanthus acidus or known as chermai has been used traditionally to treat several diseases such as fever and gum infection. This study aims to investigate the effects of Phyllanthus acidus water extract on oral bacteria and to compare its antimicrobial activities with the commercial mouthwash products in the market. In this study, two types of commercial mouthwashes which are Listerine® and Thymol solution were used to compare with Phyllanthus acidus water extract antimicrobial activities. Antimicrobial activity test was done by using broth microdilution method in a 96 wells round-bottom microtiter plate in order to determine the minimum inhibitory concentration (MIC) of Phyllanthus acidus water extract for both Staphylococcus aureus and Lactobacillus casei bacteria. The result was obtained by observing the ability of the different concentrations of extract to inhibit the growth of bacteria in the wells. From this study, both Staphylococcus aureus and Lactobacillus casei growth were fully inhibited by Phyllanthus acidus water extract at mean concentration of 3.5 mg/ml and 0.55 mg/ml respectively. The antimicrobial effects of Phyllanthus acidus water extract were comparable with the commercial mouthwashes. In conclusion, Phyllanthus acidus water extract might be used as a mouthwash as it has the ability to kill bacteria that exist in our mouth.

Metadata

Item Type: Thesis (Degree)
Creators:
Creators
Email / ID Num.
Rosli, Muhammad Shafiq
UNSPECIFIED
Contributors:
Contribution
Name
Email / ID Num.
Thesis advisor
Jalaludin, Nadia
UNSPECIFIED
Thesis advisor
Ali, Aida Azlina
UNSPECIFIED
Subjects: Q Science > QR Microbiology > Cultures and culture media. Culture technique.
R Medicine > RK Dentistry > Oral and dental medicine. Pathology. Diseases
Divisions: Universiti Teknologi MARA, Shah Alam > Faculty of Pharmacy
Programme: Bachelor of Pharmacy (Hons.)
Keywords: Antimicrobial, mouthwash, phyllanthus, microorganisms, plant extraction
Date: 2012
URI: https://ir.uitm.edu.my/id/eprint/66696
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