Comparison between High Performance Liquid Chromatography and Capillary Electrophoresis in detecting Haemoglobin Constant Spring / Muhammad Ikmal Mohd Nizar ... [et al.]

Mohamed, Emida and Mohd Nizar, Muhammad Ikmal and Raja Sabudin, Raja Zahratul Azma and Camalxaman, Siti Nazrina and Sham Rambely, Azlin and Haron, Norhisham (2019) Comparison between High Performance Liquid Chromatography and Capillary Electrophoresis in detecting Haemoglobin Constant Spring / Muhammad Ikmal Mohd Nizar ... [et al.]. Health Scope, 1. pp. 76-78. ISSN 2735-0649

Official URL: http://healthscopefsk.com/

Abstract

Two popular methods - High Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) have been compared for diagnosis of Haemoglobin Constant Spring (HbCS). The performance of the methods was evaluated in terms of sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). A total of thirty-two results were collected at HUKM which consisted of results derived from HPLC, CE and ARMS-PCR from December 2012 until December 2017. Results obtained showed CE demonstrated higher sensitivity, specificity, PPV and NPV compared to HPLC in the detection of HbCS.

Item Details

Item Type:	Article
Creators:	Creators Email / ID Num. Mohamed, Emida emida894@uitm.edu.my Mohd Nizar, Muhammad Ikmal UNSPECIFIED Raja Sabudin, Raja Zahratul Azma UNSPECIFIED Camalxaman, Siti Nazrina UNSPECIFIED Sham Rambely, Azlin UNSPECIFIED Haron, Norhisham UNSPECIFIED
Subjects:	Q Science > QD Chemistry > Analytical chemistry Q Science > QP Physiology > Animal biochemistry > Electrophoresis
Divisions:	Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Health Sciences
Journal or Publication Title:	Health Scope
UiTM Journal Collections:	Other UiTM Journals > Healthscope
ISSN:	2735-0649
Volume:	1
Page Range:	pp. 76-78
Keywords:	Capillary Electrophoresis, Haemoglobin Constant Spring (HbCS), High Performance Liquid Chromatography
Date:	June 2019
URI:	https://ir.uitm.edu.my/id/eprint/54674

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