Chemical composition and biological activity of Momordica Charantia (Bitter Melon) / Rohaiza Saat … [et al.]

Saat, Rohaiza and Razak, Nur Hazwani and Rosly, Nurasyikin and Ishak, Siti Zulaikha (2021) Chemical composition and biological activity of Momordica Charantia (Bitter Melon) / Rohaiza Saat … [et al.]. In: International Jasin Multimedia & Computer Science Invention and Innovation Exhibition (i-JaMCSIIX 2021). UiTM Cawangan Melaka Kampus Jasin, pp. 63-65.

Abstract

Phytochemical analysis and biological activities of Momordica charantia have been studied. Two parts of plant were used in this study such as fruit and seed. Plant sample has been extracted by using three different polarity of solvents such as n-hexane, chloroform and methanol through the cool extraction method. The result has shown that the highest percentage yield was methanol fruit extract with 15.29%. The phytochemical analysis has revealed there are many secondary metabolites in M. charantia fruit and seed such as alkaloid, flavonoid, saponin, phenol, tannin, terpenoid, steroid and glycoside while for seed part saponin was absence. Antibacterial study has been conducted by using disc diffusion method on Bacillus subtilis, Staphylococcus aureus, Salmonella typhimurium and Escherichia coli. In addition, the result has shown that the highest inhibition zone for fruit and seed was on Staphylococcus aureus in the range of 16 to 17 mm. Meanwhile, the antioxidant study revealed that the fruit and seed of M. charantia do not have antioxidant activity with percentage inhibition less than 50%. The results of this study conclude that M. charantia extract contains medicinally important bioactive compounds with efficient biological activities.

Metadata

Item Type: Book Section
Creators:
Creators
Email / ID Num.
Saat, Rohaiza
rohaizas@uitm.edu.my
Razak, Nur Hazwani
UNSPECIFIED
Rosly, Nurasyikin
UNSPECIFIED
Ishak, Siti Zulaikha
UNSPECIFIED
Contributors:
Contribution
Name
Email / ID Num.
Patron
Md Badarudin, Ismadi
UNSPECIFIED
Advisor
Tahar @ Yusoff, Nor Fadilah
UNSPECIFIED
Advisor
Jono, Mohd Nor Hajar Hasrol
UNSPECIFIED
Advisor
Abdul Rahid @ Abdul Rashid, Nurul Najwa
UNSPECIFIED
Advisor
Sharip, Anis Afiqah
UNSPECIFIED
Subjects: Q Science > QH Natural history - Biology > Biology
Q Science > QH Natural history - Biology > Bioactive compounds
Q Science > QV Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > Anti-inflammatory agents (General or not elsewhere classified)
Divisions: Universiti Teknologi MARA, Melaka > Jasin Campus > Faculty of Computer and Mathematical Sciences
Event Title: International Jasin Multimedia & Computer Science Invention and Innovation Exhibition (i-JaMCSIIX 2021)
Event Dates: 15 February 2021 - 31 March 2021
Page Range: pp. 63-65
Keywords: Momordica charantia; Chemical composition; Antibacterial; Antioxidant
Date: 2021
URI: https://ir.uitm.edu.my/id/eprint/50616
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