Chemical composition and biological activity of Momordica Charantia (Bitter Melon) / Nurasyikin Rosly … [et al.]

Rosly, Nurasyikin and Saat, Rohaiza and Ishak, Siti Zulaikha and Razak, Nur Hazwani (2021) Chemical composition and biological activity of Momordica Charantia (Bitter Melon) / Nurasyikin Rosly … [et al.]. In: International Jasin Multimedia and Computer Science Invention and Innovation Exhibition (i-JaMCSIIX 2021). International Jasin Multimedia and Computer Science Invention and Innovation Exhibition, 4 . Faculty of Computer and Mathematical Sciences, Jasin, p. 39.

Abstract

Phytochemical analysis and biological activities of Momordica charantia have been studied. Two parts of plant were used in this study such as fruit and seed. Plant sample has been extracted by using three different polarity of solvents such as n-hexane, chloroform and methanol through the cool extraction method. The result has shown that the highest percentage yield was methanol fruit extract with 15.29%. The phytochemical analysis has revealed there are many secondary metabolites in M. charantia fruit and seed such as alkaloid, flavonoid, saponin, phenol, tannin, terpenoid, steroid and glycoside while for seed part saponin was absence. Antibacterial study has been conducted by using disc diffusion method on Bacillus subtilis, Staphylococcus aureus, Salmonella typhimurium and Escherichia coli. In addition, the result has shown that the highest inhibition zone for fruit and seed was on Staphylococcus aureus in the range of 16 to 17 mm. Meanwhile, the antioxidant study revealed that the fruit and seed of M. charantia do not have antioxidant activity with percentage inhibition less than 50%. The results of this study conclude that M. charantia extract contains medicinally important bioactive compounds with efficient biological activities.

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Item Type: Book Section
Creators:
Creators
Email / ID Num.
Rosly, Nurasyikin
UNSPECIFIED
Saat, Rohaiza
rohaizas@uitm.edu.my
Ishak, Siti Zulaikha
UNSPECIFIED
Razak, Nur Hazwani
UNSPECIFIED
Subjects: Q Science > QH Natural history - Biology > Biology
Q Science > QH Natural history - Biology > Bioactive compounds
Q Science > QV Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > Anti-inflammatory agents (General or not elsewhere classified)
Divisions: Universiti Teknologi MARA, Melaka > Jasin Campus > Faculty of Computer and Mathematical Sciences
Series Name: International Jasin Multimedia and Computer Science Invention and Innovation Exhibition
Volume: 4
Page Range: p. 39
Keywords: Momordica charantia; Chemical composition; Antibacterial; Antioxidant
Date: 2021
URI: https://ir.uitm.edu.my/id/eprint/49545
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