Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar

Abdul Aziz, Mardiana Abdul Aziz and Omar, Effat Omar (2020) Pyogenic granuloma-like Kaposi sarcoma: Case report and review of literature / Mardiana Abdul Aziz and Effat Omar. Journal of Clinical and Health Sciences, 5 (2). pp. 66-74. ISSN 0127 – 984X

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Abstract

Pyogenic granuloma-like Kaposi sarcoma (PGLKS) is an uncommon variant of Kaposi sarcoma (KS), which mimics benign pyogenic granuloma both clinically and histologically. We report a case of PGLKS of the toe occurring in a HIV-positive individual. It presented as a 2cm skin swelling of 2 weeks’ duration which was clinically felt to be a pyogenic granuloma. Histopathological examination revealed a polypoid atypical vascular lesion with overlying peripheral epidermal collarette. Spindle cell proliferation typically seen in KS was also identified, which was positive for human herpesvirus 8 (HHV8) by immunohistochemistry, confirming the diagnosis of PGLKS. Upon review of the literature, our case is the 29th case of PGLKS reported to date, and only the sixth in Asian population. Particular attention to histomorphology, and demonstration of HHV8 in lesional tissue will aid accurate diagnosis of this rare entity.

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Item Type: Article
Creators:
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Abdul Aziz, Mardiana Abdul Aziz
UNSPECIFIED
Omar, Effat Omar
UNSPECIFIED
Subjects: R Medicine > RB Pathology
R Medicine > RC Internal Medicine > Neoplasms. Tumors. Oncology
Divisions: Universiti Teknologi MARA, Selangor > Puncak Alam Campus > Faculty of Medicine
Journal or Publication Title: Journal of Clinical and Health Sciences
UiTM Journal Collections: UiTM Journal > Journal of Clinical and Health Sciences (JCHS)
ISSN: 0127 – 984X
Volume: 5
Number: 2
Page Range: pp. 66-74
Official URL: https://jchs-medicine.uitm.edu.my/index.php
Item ID: 44193
Uncontrolled Keywords: Kaposi sarcoma, pyogenic granuloma, human herpesvirus 8, human immunodeficiency virus, histopathology
URI: https://ir.uitm.edu.my/id/eprint/44193

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44193

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