Phytochemical analysis of citrus maxima and its effect on male reproductive system in high-fat diet induced sprague dawley rats / Farah Amna Othman ... [et al.]

Othman, Farah Amna and Syed Mohamad, Syarifah Faezah and Sabarudin, Nur Aalia Adilah and Ajit, Nurul Nadia (2018) Phytochemical analysis of citrus maxima and its effect on male reproductive system in high-fat diet induced sprague dawley rats / Farah Amna Othman ... [et al.]. Gading Journal for Science and Technology, 1 (1). pp. 95-104. ISSN 2637-0018

Abstract

Present study was designed to evaluate phytochemical constituents, hypoglycemic effect and the juice effect of Citrus maxima on sperm quality. In phytochemical screening, the juices were tested for availability of reducing sugar, flavonoid, antraquinone, tannins, terpenoid, saponin and alkaloid. In animal study, the rats were subjected to high fat diet for 6 weeks to induce obesity and hyperglycemic. The rats were then divided into 3 groups (n=6); control, HFD and CM groups. The results obtained demonstrated that C. maxima juice possessed reducing sugars, terpenoids, and saponins. Body weight in CM group increased significantly (p≤0.05) throughout the treatment period. Sperm count was higher in the CM group as compared to HFD group, even though the differences were not significant. HFD group showed significant decrease (p≤0.05) in progressive motility (PM) sperms, highest percent in non-progressive motility (NPM) and non motile (NM) sperms compared to control group. HFD and CM groups showed significant decreased in normal sperm compared to control group, where CM group showed better result compared to HFD group. HFD displayed significant decrease (p≤0.05) in blood glucose level compared to control group. It was concluded that the adverse effects of HFD on male reproductive system can be reversed by treatment with C. maxima juices, where it also displayed antihyperglycemic and anti-obesity effects

Metadata

Item Type: Article
Creators:
Creators
Email / ID Num.
Othman, Farah Amna
farahamna@pahang.uitm.edu.my
Syed Mohamad, Syarifah Faezah
UNSPECIFIED
Sabarudin, Nur Aalia Adilah
UNSPECIFIED
Ajit, Nurul Nadia
UNSPECIFIED
Subjects: Q Science > QK Botany > Plant physiology > Botanical chemistry. Phytochemicals
Q Science > QV Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > Anti-inflammatory agents (General or not elsewhere classified)
S Agriculture > SB Plant culture > Medicinal plants (Culture only)
Divisions: Universiti Teknologi MARA, Pahang > Jengka Campus
Journal or Publication Title: Gading Journal for Science and Technology
UiTM Journal Collections: UiTM Journal > Gading Journal of Science and Technology (GADINGS&T)
ISSN: 2637-0018
Volume: 1
Number: 1
Page Range: pp. 95-104
Keywords: Citrus maxima, Reproductive system, High-fat diet, Phytochemical analysis
Date: 27 September 2018
URI: https://ir.uitm.edu.my/id/eprint/31358
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