Antibacterial and antioxidant properties of shorea sumatrana leaves / Tazkeerah Hasanah Awang Said

Awang Said, Tazkeerah Hasanah (2015) Antibacterial and antioxidant properties of shorea sumatrana leaves / Tazkeerah Hasanah Awang Said. [Student Project] (Submitted)

Abstract

The timber value of Shorea sumatrana has been well known from decades. Shorea is a major exotic species found in tropical regions and they are one of the endemic plants in Malaysia. This study is aimed to evaluate the antibacterial and antioxidant properties of the methanol extract of Shorea sumatrana leaves. The antibacterial activity of the methanol extract of S. sumatrana was assessed against gram-positive and gram-negative bacteria by disc diffusion method. On the other hand, the antioxidant activity was detected by DPPH radical scavenging activity. In the preliminary screening experiment of antibacterial activity, all of the tested bacteria showed varying degrees of sensitivity to the leaves extracts excluding P. aeruginosa. Results obtained that S. epidermidis, a gram-positive bacterium as the most susceptible to the extracts of leaves at the applied doses. Besides, only P. aeruginosa was resistant to the extracts. My findings clearly demonstrate that the leaves extracts of S. sumatrana had strong antibacterial effects and raises the possibility of using the extracts as antibacterial agents in treating pathological conditions caused by bacteria infection. Although the effect of S. sumatrana leaves against some pathogenic bacteria in vitro is promising, further microbiological and pharmacological studies will be required. In present study, in vitro antioxidant activities of the methanolic extracts of leaves of S. sumatrana were determined by spectrophotometric methods. Antioxidant activities of extract were expressed as percentage of DPPH radical inhibition. The methanolic extract of S. sumatrana leaves showed maximum antioxidant activity of 98.87% at 500 pg/ml concentration. Thus, this study reveals that leaves of S. sumatrana has a potential as a natural sources of antioxidant.

Metadata

Item Type: Student Project
Creators:
Creators
Email / ID Num.
Awang Said, Tazkeerah Hasanah
UNSPECIFIED
Subjects: Q Science > QD Chemistry > Extraction (Chemistry)
Q Science > QR Microbiology > Bacteria
Divisions: Universiti Teknologi MARA, Negeri Sembilan > Kuala Pilah Campus > Faculty of Applied Sciences
Keywords: Antibacterial, and antioxidant properties, of shorea sumatrana leaves, UiTM Negeri Sembilan
Date: 2015
URI: https://ir.uitm.edu.my/id/eprint/25134
Edit Item
Edit Item

Download

[thumbnail of PPb_TAZKEERAH HASANAH AWANG SAID AS N 15_5.pdf] Text
PPb_TAZKEERAH HASANAH AWANG SAID AS N 15_5.pdf

Download (90kB)

Digital Copy

Digital (fulltext) is available at:

Physical Copy

Physical status and holdings:
Item Status:

ID Number

25134

Indexing

Statistic

Statistic details