Isolation and phytochemical investigation of antioxidative from the curcuma longa leaves / Nurhidayah Osman

Curcuma longa leaves were applied in cosmetics, food additive and
medicinal purpose. Curcuma longa leaves contains secondary metabolites
of terpenoids which have been found in antioxidant properties. Based on
experiments isolated compound from petroleum ether extract done by GCMS
found the suggested structure of antioxidative components are
Benzene, (2,4cyclopentadien-1-ylidenemethyl), Estra-I ,3,5( I0)-trien-17ᵝ01,
Benzene, 1,3-dimethyl, Hexadecanoic acid, methyl ester, IH-Indene, 1methylene,
Hexadecanoic acid, 1-(hydroxymethyl)-1,2-ethanediyl ester,
Cyclopentanol, I-methyl and Triphenylphosphine oxide. While,
scavenging activity of extract Curcuma longa leaves on DPPH radicals
IC50 value to perform antioxidant properties, it is showed the
dichloromethane has the strongest scavenging activity (IC50 > 6.25 µg /
ml) compared with petroleum ether extract (lC50 > 100 µg / ml) and
methanol extract (IC50 > 100 µg / ml). As Curcuma longa leaves has
antioxidant properties it has potential for the development of modem
medicine for the treatment of various diseases.