Phytochemical screening, antifungal and antibacterial activity of methanol, ethyl acetate and hexane extracts in the root of pithecellobium jiringa / Nur Izyan Jamil

The aim of this study is to investigate the phytochemical screening, antifungal and
antibacterial activity of methanol, ethyl acetate and hexane extracts in the root of
Pithecellobium Jiringa (P.jiringa). The study on phytochemical screening was revealed
the presence of important secondary metabolites which are tannins, flavonoids,
terpenoids and saponins in the root hence indicating the medicinal potentials of the
plant. The study was investigated on antibacterial activity with bacteria Staphylococcus
aureus and Staphylococcus epidermidis while Candida albicans for the antifungal
activity. The results showed that the methanol crude extract of the root P.jiringa
exhibited marked antimicrobial effects on Staphylococcus aureus, Staphylococcus
epidermidis and Candida albicans. For antibacterial activity, the highest inhibition zone
of methanol extract is 15 rom at 200 mg/mL and antifungal activity is weakly inhibition
at 200 mg/mL with only 8.77 rom diameter of inhibition zone. The ethyl acetate extract
show no inhibition zone on the antifungal activity. From bioautography assay the
compound towards S.aureus, S. epidermidis and C. albicans are flavonoid and tannin.
This study proves that P.jiringa root has a potential source of active antimicrobial
agents.