Anti-diabetic effect of apple vinegar in alloxan-induced diabetic rats / Siti Maisarah Abdullah

Apple vinegar has widely been used as antidiabetic effect due to the ability to
reduce the blood glucose level. The objective of this work is to evaluate the effect
dietary of apple vinegar in body weight and blood glucose level in alloxan induced
diabetic rats. 5 Wistar male rats were divided into 5 different groups
which are distilled water, 0.16 ml apple vinegar, 0.18 ml apple vinegar, 0.2 ml
apple vinegar and metformin. All the treatment were delivered through oral
gavage every day before meal time. The daily food and drink uptake in all groups
are controlled and fixed. The blood glucose level and body weight were measured
once in 3 days for 15 days. In apple vinegar treatment groups, the consumption
caused decreased of blood glucose level and body weight. There is significant
difference in blood glucose level but not for body weight. Meanwhile, in distilled
water group there is only slight decreased of blood glucose level and body weight.
Metformin decreased both blood glucose level and body weight. However, there is
some fluctuation in blood glucose level and body weight that might be caused by
the amount of food and water uptake. It is concluded that apple vinegar can reduce
blood glucose level and body weight in alloxan-induced rats.