Triglyceride-glucose index: a practical but partial surrogate of insulin resistance in children with obesity

Childhood obesity is strongly associated with insulin resistance (IR) and the early development of cardiometabolic complications. However, direct assessment of IR using gold-standard methods is impractical in large paediatric population studies. The triglyceride–glucose (TyG) index, derived from fasting triglyceride and glucose concentrations, has emerged as a simple surrogate marker of IR in adults, but evidence in children, particularly those with obesity, remains limited. This study aims to determine the correlation between the TyG index and HOMA-IR and other IR–related markers in children with obesity.