Abstract
During the past lew decades there has been an increasing interest in the development of biodegradable mkro/nanoparticles as drug delivery devices. Previous studies have reported that some existing additives are expensive and have poor degradability. The use of edible-based biodegradable additive remains attractive because of their abundance in nature and cost-effective. Biodegradable micro and nano-partkulate additive is proposed. Selected local additive produced locally is incorporated with Metformin drug. Characterization, physical study and biological study was attempted, such as determination, morphological and Theological test, drug loading capabilities, biodegradation, toxicity and in vitro studies. The focus of the study is to create local biodegradable micro- and nano-snxd particulate additive with Metformin loading formulation theory for drug delivery system. Apart from that, formulation theory created purposely aims to support the Malaysia's NKEA in healthcare so that focal generic manufacturing for export can be increases.
Metadata
| Item Type: | Article |
|---|---|
| Creators: | Creators Email / ID Num. Hashim, Muhammad Hisyam UNSPECIFIED Husin, Hazlina UNSPECIFIED |
| Subjects: | R Medicine > RS Pharmacy and materia medica > Materia medica > Pharmaceutical chemistry T Technology > TP Chemical technology > Biotechnology |
| Divisions: | Universiti Teknologi MARA, Shah Alam > Faculty of Chemical Engineering |
| Page Range: | pp. 1-5 |
| Keywords: | Biodegradable, Micro/nanopartides, Drug delivery devices, Drug carrier, Metformin drug, Diabetes, Costeffective, Natural-based, Locally available |
| Date: | February 2018 |
| URI: | https://ir.uitm.edu.my/id/eprint/134634 |
