Solubility enhancement of poorly water-soluble compounds: article

This study was undertaken to evaluate the potential of maltodextrin to enhance solubility in drug delivery in the encapsulation of Mentha x Piperita essential oil by spray drying method. Menta x Piperita essential oils was encapsulated with only combination of maltodextrin and gum Arabic (GA) in order to achieve maximum encapsulation performance. Sodium dodecyl sulfate was added to investigate the interactions with encapsulated Menta x Piperita. The performance of the Menta x Piperita essential oils encapsulation was evaluated by fourier transform infrared (FT-IR) spectroscopy and thermal transition properties (DSC). The combination of both materials (maltodexrin and gum Arabic) was considered a successful encapsulation for Menta x Piperita essential oil.