Complexation of schiff base ligands: synthesis, characterization and antimicrobial studies / Suhaili Zainal Abidin

Two new Schiff base ligands were prepared by condensation reaction of benzaldehyde or chlorobenzaldehyde with ethylenediamine in the 2:1 ratio. The two Schiff base ligands were obtained were N,N’-bis-(4-chloro-benzylidene)-ethane -1,2-diamine and N,N’-dibenzylidene-ethane-1,2-diamine. The Schiff base complexes of N,N’-bis-(4-chloro-benzylidene)-ethane-1,2-diamine with Ni(II), Cu(II) and Co(III) have been successfully prepared. The Schiff base complexes were prepared by the template method. Tentative structures are proposed for the ligands and complexes by elemental analysis, magnetic susceptibility, FTIR and 1HNMR. The antibacterial and antifungal activities were studiedusing disc diffusion method against Escherichia coli,Enterococcus faecalis and Candida albicans, respectively. The metal complexes showed more inhibition compared to the ligands.